Coeliac Disease Study

Coeliac Disease is an autoimmune disorder that develops in genetically predisposed people. It involves an immune response to gluten containing foods such as wheat, barley and rye found in bread, cereals, pasta and baked goods. 

The only current treatment is to maintain a lifelong, strict gluten free diet which can be extremely challenging. The inevitable breaks in the diet result in uncomfortable symptoms such as diarrhoea, abdominal pain and bloating that disrupt everyday life. On top of this, availability of gluten free food varies between countries and regions and the cost is significantly higher than equivalent gluten containing food. 

As such, there is significant unmet medical need for safe and effective alternative treatments in addition to dietary avoidance of gluten.

This research study is evaluating the efficacy of an investigational treatment to understand whether it has potential to be an effective treatment for people with coeliac disease. The study will look at the impact the potential treatment has on outcomes such as gastrointestinal issues and coeliac disease associated autoantibodies. 

Participants will receive either the active study treatment or a placebo (non- active substance that looks identical to study treatment. Some participants will undergo a gluten challenge to evaluate the effectiveness of the study treatment after gluten exposure. During the study, participants will receive ongoing health monitoring and assessments. 

Register your interest now to find out if you are eligible to participate in this study and help develop potential new treatment options for people living with coeliac disease.